Jameson Research

We studies the factors that regulate the survival and activation of mature T-cells in the peripheral lymphoid system that engage in immune responses. An area of his current research interest is learning how vaccines work in the T-cell context. In experimental studies in mice, he and his colleagues applied vaccines to skin to see whether epicutaneous application was sufficient to generate an effective memory CD8 T-cell response that would be protective against bacterial and viral infection. Though somewhat less protective than injected or oral vaccine, epicutaneous immunization using adhesive bandages could potentially be used in developing countries due to the ease of application.